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Puffing behaviors vary and comparisons are rough, but inhaling vapor from 3 milliliters of e-liquid is similar to smoking 30 to 40 conventional cigarettes, or a pack and a half to two packs, in terms of number of puffs

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The latest study found that overexpression of mesencephalic astrocyte-derived neurotrophic factor (MANF), a secreted protein belonging to growth factors, ameliorated defective mitophagy and reduced cGAS-STING activation, which inhibited renal interstitial fibrosis (Zhu et al., 2022)

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